Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.68 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.68 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.68 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.68 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 9/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27212832 | 0.81 | NPC1 (1.00) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL11522924 | 0.79 | NPC1 (0.60) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL11519135 | 0.77 | NPC1 (0.58) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL11523235 | 0.76 | MAPT (0.60) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL11430427 | 0.76 | MAPK8 (0.79) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL11523201 | 0.75 | MAPT (0.55) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL8050359 | 0.75 | NPC1 (0.55) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL11521972 | 0.74 | NPC1 (0.54) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL11883361 | 0.74 | MAPK8 (0.58) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL8050086 | 0.72 | MAPK8 (0.52) | NPC1RAB9AALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174394-A | CONTROL OF BACTERIA AND FUNGI | THE DOW CHEMICAL COMPANY (US) | 1979-11-13 | — | — | US | claimed |
| US-4174394-A | CONTROL OF BACTERIA AND FUNGI | THE DOW CHEMICAL COMPANY (US) | 1979-11-13 | — | — | US | disclosed |