Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 9/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11504495 | 0.78 | MAPK8 (0.54) | MAPTNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL11518318 | 0.77 | NPC1 (0.49) | MAPTNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL11523235 | 0.75 | MAPT (0.60) | MAPTNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL11519332 | 0.75 | NPC1 (0.68) | MAPTNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL11430427 | 0.74 | MAPK8 (0.79) | MAPTNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL11504699 | 0.74 | MAPK8 (0.50) | MAPTNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL11495617 | 0.73 | MAPK8 (0.52) | MAPTNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL11883361 | 0.73 | MAPK8 (0.58) | MAPTNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL11522924 | 0.72 | NPC1 (0.60) | MAPTNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL8050359 | 0.71 | NPC1 (0.55) | MAPTNPC1RAB9ANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174394-A | CONTROL OF BACTERIA AND FUNGI | THE DOW CHEMICAL COMPANY (US) | 1979-11-13 | — | — | US | claimed |
| US-4174394-A | CONTROL OF BACTERIA AND FUNGI | THE DOW CHEMICAL COMPANY (US) | 1979-11-13 | — | — | US | disclosed |