Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6010347 | 0.79 | OR51E2 (0.37) | TP53SMPD2OR51E2 | |
| SCHEMBL6010362 | 0.79 | OR51E2 (0.37) | TP53SMPD2OR51E2 | |
| SCHEMBL28244250 | 0.78 | TP53 (0.39) | TP53BLMGABRR1RNPEPCYP1A2 | |
| SCHEMBL304130 | 0.74 | HTR2A (0.52) | TP53SMPD2PGRADRA2AADRA2B | |
| SCHEMBL10207211 | 0.74 | HTR2A (0.52) | TP53SMPD2PGRADRA2AADRA2B | |
| SCHEMBL172237 | 0.74 | HTR2A (0.52) | TP53SMPD2PGRADRA2AADRA2B | |
| SCHEMBL20312073 | 0.73 | SMPD2 (0.41) | TP53SMPD2PGRADRA2AADRA2B | |
| SCHEMBL24711911 | 0.73 | ENPEP (0.35) | TP53BLMRNPEP | |
| SCHEMBL22667826 | 0.73 | TP53 (0.35) | TP53CYP1A2 | |
| SCHEMBL27937766 | 0.73 | TP53 (0.35) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143159-A | SKIN-CARE AGENTS CONTAINING HYDROXYALKYL CARBOXAMIDES AND PROCESS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1979-03-06 | — | — | US | claimed |