Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563273 | 0.91 | MEN1 (0.68) | MEN1OPRM1KMT2AOPRD1ADRB3 | |
| SCHEMBL7606856 | 0.90 | MEN1 (0.63) | MEN1OPRM1KMT2AOPRD1ADRB3 | |
| SCHEMBL11519687 | 0.86 | PTGS1 (0.56) | ADRB3ADRB1ADRB2SLC6A2PTGS1 | |
| SCHEMBL11606524 | 0.84 | MEN1 (0.71) | MEN1OPRM1KMT2AOPRD1ADRB3 | |
| SCHEMBL11517228 | 0.84 | ADRB3 (0.53) | MEN1KMT2AADRB3ADRB1ADRB2 | |
| SCHEMBL7610416 | 0.83 | MEN1 (0.84) | MEN1OPRM1KMT2AOPRD1ADRB3 | |
| SCHEMBL22289126 | 0.81 | HIF1A (0.57) | MEN1OPRM1KMT2AKDM4ECYP2D6 | |
| SCHEMBL11517619 | 0.81 | ATM (0.55) | MEN1OPRM1KMT2AOPRD1ADRB3 | |
| SCHEMBL20049939 | 0.80 | MEN1 (0.75) | MEN1OPRM1KMT2AOPRD1ADRB3 | |
| SCHEMBL9320639 | 0.80 | ADRB2 (0.74) | MEN1OPRM1KMT2AOPRD1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146638-A | CARDIOTONIC, VASODILATION, HYPOTENSIVE, ANTIARRYTHMIA AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |