Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL1886510 | 0.80 | — | — | |
| Diethanolamine SCHEMBL1011320 | 0.80 | — | — | |
| Diethanolamine SCHEMBL28666648 | 0.80 | ALDH1A1 (0.50) | LMNAKDM4EMAPK1TSHR | |
| Diethanolamine SCHEMBL27661740 | 0.79 | TSHR (0.32) | LMNAKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL6898883 | 0.78 | — | — | |
| Diethanolamine SCHEMBL11849912 | 0.77 | SMN1; SMN2 (0.33) | LMNASMN1; SMN2KDM4EMAPK1TSHR | |
| Diethanolamine SCHEMBL5391215 | 0.77 | — | — | |
| Diethanolamine SCHEMBL901546 | 0.77 | — | — | |
| Diethanolamine SCHEMBL28826340 | 0.77 | SMN1; SMN2 (0.33) | LMNASMN1; SMN2KDM4EMAPK1TSHR | |
| Hydrochloric Acid SCHEMBL650652 | 0.77 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2KDM4EMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145547-A | Ureidoalkylphosphonates and their use for the flameproofing of textiles | STAUFFER CHEMICAL COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4044006-A | FLAME RESISTANCE | STAUFFER CHEMICAL COMPANY (US) | 1977-08-23 | — | — | US | disclosed |