SCHEMBL11519581

SCHEMBL11519581

COC(=O)COP(C)(=O)O

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.42
HSD17B10 Q99714 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SAT1 P21673 1/20 0.37
TPI1 P60174 1/20 0.37
POLB P06746 1/20 0.34
LMNA P02545 2/20 0.33
TET2 Q6N021 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CA2 P00918 1/20 0.32
CA12 O43570 1/20 0.31
CA14 Q9ULX7 1/20 0.31
KDM4E B2RXH2 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10011806 0.83 TSHR (0.43) TSHRHSD17B10MGAMGAASI
SCHEMBL11519577 0.83 TSHR (0.43) TSHRHSD17B10MGAMGAASI
SCHEMBL10067496 0.83 TPI1 (0.54) TSHRHSD17B10MGAMGAASI
SCHEMBL10011067 0.79 TSHR (0.40) TSHRHSD17B10MGAMGAASI
SCHEMBL4004535 0.77 TSHR (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL10010047 0.76 TSHR (0.42) TSHRHSD17B10MGAMGAASI
SCHEMBL11660841 0.76 MEN1 (0.38) TSHRHSD17B10MGAMGAASI
SCHEMBL10011397 0.76 CA12 (0.37) TSHRHSD17B10MGAMGAASI
SCHEMBL14299134 0.75
SCHEMBL10388724 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4177300-A PHOSPHONATE, AMINO RESIN, ACID CATALYST, CURING, FOR TEXTILES STAUFFER CHEMICAL COMPANY (US) 1979-12-04 US disclosed
US-4162279-A FLAME RETARDANTS FOR TEXTILES STAUFFER CHEMICAL COMPANY (US) 1979-07-24 US disclosed