SCHEMBL11519892

SCHEMBL11519892

CCCCOCCOC(CC(C)=O)C(=O)OCC

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
CES2 O00748 1/20 0.39
TSHR P16473 4/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 2/20 0.34
HSD17B10 Q99714 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
THRB P10828 2/20 0.33
ATM Q13315 1/20 0.33
HTT P42858 1/20 0.33
RARB P10826 1/20 0.33
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
HPGD P15428 1/20 0.32
LMNA P02545 1/20 0.31
PLA2G2C Q5R387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22471906 0.88 ALDH1A1 (0.37) ALDH1A1TSHRCYP3A4MAPTHSD17B10
SCHEMBL11521400 0.87 ALDH1A1 (0.47) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL27825817 0.80 ALDH1A1 (0.39) ALDH1A1TSHRMEN1KMT2AATM
SCHEMBL8336122 0.78 AKR1B1 (0.38) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL8090817 0.75 MEN1 (0.44) ALDH1A1TSHRCYP3A4MAPTMEN1
SCHEMBL7616354 0.74 ALDH1A1 (0.43) ALDH1A1TSHRCYP3A4HSD17B10MEN1
SCHEMBL14252257 0.73 TSHR (0.41) ALDH1A1CES2TSHRCYP3A4MAPT
SCHEMBL29264259 0.73 MEN1 (0.35) ALDH1A1HSD17B10MEN1KMT2ALMNA
SCHEMBL16631559 0.72 LPAR1 (0.40) ALDH1A1TSHRCYP3A4MAPTHSD17B10
Methyl Isobutyl Ketone SCHEMBL8028996 0.72 ALDH1A1 (0.58) ALDH1A1CES2TSHRCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4147686-A VINYL CHLORIDE RESIN, OXALATES ARMSTRONG CORK COMPANY (US) 1979-04-03 US disclosed
US-4085081-A \"Smoke-suppressant polyhalocarbon polymer compositions containing as plasticizer an unsaturated derivative of an ester polyol\ ARMSTRONG CORK COMPANY (US) 1978-04-18 US disclosed