Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519108 | 0.96 | GAA (0.44) | GAATDP1ALDH1A1NR5A2NR5A1 | |
| SCHEMBL11518677 | 0.92 | GAA (0.54) | GAATDP1ALDH1A1NR5A2NR5A1 | |
| SCHEMBL11521372 | 0.88 | TDP1 (0.46) | GAATDP1ALDH1A1CNR1KMT2A | |
| SCHEMBL11522501 | 0.87 | GAA (0.56) | GAATDP1ALDH1A1NR5A2NR5A1 | |
| SCHEMBL11520610 | 0.86 | GAA (0.55) | GAATDP1ALDH1A1NR5A2NR5A1 | |
| SCHEMBL9807633 | 0.85 | GAA (0.69) | GAATDP1ALDH1A1KMT2ALMNA | |
| SCHEMBL11518542 | 0.85 | TDP1 (0.41) | GAATDP1ALDH1A1CNR1RECQL | |
| SCHEMBL11518156 | 0.85 | TDP1 (0.43) | GAATDP1ALDH1A1CNR1KMT2A | |
| SCHEMBL11520930 | 0.83 | GAA (0.49) | GAATDP1ALDH1A1KMT2ALMNA | |
| SCHEMBL11519609 | 0.81 | GAA (0.47) | GAATDP1ALDH1A1LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152319-A | ALPHA, BETA-UNSATURATED AMIDES HAVING STERICALLY HINDERED PHENOLIC GROUP | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-05-01 | — | — | US | disclosed |