Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.42 |
| ▸ | GLRB | P48167 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522501 | 0.90 | GAA (0.56) | GAATDP1ALDH1A1CA2CA1 | |
| SCHEMBL11520610 | 0.89 | GAA (0.55) | GAATDP1ALDH1A1CA2CA1 | |
| SCHEMBL11518677 | 0.87 | GAA (0.54) | GAATDP1ALDH1A1CA2CA1 | |
| SCHEMBL11519989 | 0.85 | GAA (0.51) | GAATDP1ALDH1A1CA2CA1 | |
| SCHEMBL11520550 | 0.84 | GAA (0.49) | GAATDP1ALDH1A1RXFP1POLB | |
| SCHEMBL11520930 | 0.84 | GAA (0.49) | GAATDP1ALDH1A1RXFP1POLB | |
| SCHEMBL11519609 | 0.83 | GAA (0.47) | GAATDP1ALDH1A1RXFP1POLB | |
| SCHEMBL9812317 | 0.82 | GAA (0.68) | GAATDP1ALDH1A1CA2CA1 | |
| SCHEMBL2276660 | 0.82 | GAA (1.00) | GAATDP1ALDH1A1CA2CA1 | |
| SCHEMBL22281120 | 0.82 | ALDH1A1 (0.67) | GAATDP1ALDH1A1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990671-A | Method for making aminophenols and their amide derivatives | MALLINCKRODT, INC. (US) | 1991-02-05 | — | — | US | disclosed |
| EP-0028999-B1 | PROCESS FOR THE PREPARATION OF ANTIOXIDANT AMIDES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-03-23 | — | — | EP | disclosed |
| US-4286105-A | AMIDATION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-08-25 | — | — | US | disclosed |
| US-4281080-A | TACKIFIERS FOR RUBBERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| EP-0028999-A1 | Process for the preparation of antioxidant amides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-05-20 | — | — | EP | disclosed |
| US-4173574-A | 3,5-Ditertiary alkyl-4-hydroxyphenyl (alkyl) 6-acyloxy-4-thia hexanoates and hexenamides as antioxidants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-11-06 | — | — | US | disclosed |
| US-4152319-A | ALPHA, BETA-UNSATURATED AMIDES HAVING STERICALLY HINDERED PHENOLIC GROUP | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4093591-A | FOR NATURAL RUBBER AND HOMO- AND COPOLYMERS OF MONO- AND DIOLEFINS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-06-06 | — | — | US | disclosed |
| US-4010140-A | Age resistant resin compositions and admixtures useful as adhesives | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-03-01 | — | — | US | disclosed |