Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35604 | 0.88 | ALDH1A1 (0.41) | MAPK1ALDH1A1MAPTTSHR | |
| SCHEMBL28125944 | 0.88 | ALDH1A1 (0.41) | MAPK1ALDH1A1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL2141340 | 0.85 | ALDH1A1 (0.39) | MAPK1ALDH1A1MAPTTSHR | |
| Water SCHEMBL29144646 | 0.85 | ALDH1A1 (0.39) | MAPK1ALDH1A1MAPTTSHR | |
| SCHEMBL27982432 | 0.85 | ALDH1A1 (0.39) | MAPK1ALDH1A1MAPTTSHR | |
| Ammonia Solution, Strong SCHEMBL27816809 | 0.85 | ALDH1A1 (0.39) | MAPK1ALDH1A1MAPTTSHR | |
| Boric Acid SCHEMBL28247839 | 0.81 | ALDH1A1 (0.36) | MAPK1ALDH1A1TSHR | |
| SCHEMBL5959239 | 0.79 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| Acetic Acid SCHEMBL11209922 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL28218892 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165331-A | PROSTAGLANDINS/AND DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4154959-A | 11-(2-Hydroxyethylthio)prostenoic acid E series derivatives | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4052552-A | THROMBOXANE B ANALOGS | THE UPJOHN COMPANY (US) | 1977-10-04 | — | — | US | disclosed |