Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2210061 | 0.98 | MAPT (0.34) | MAPTSLC22A16TSHRCHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL204257 | 0.96 | MAPT (0.38) | MAPTSLC22A16TSHRCHRM2CHRM4 | |
| Sulfuric Acid SCHEMBL11519848 | 0.87 | SLC22A16 (0.36) | MAPTSLC22A16TSHRCHRM2CHRM4 | |
| Phosphoric Acid SCHEMBL8763232 | 0.87 | SMN1; SMN2 (0.36) | MAPTSLC22A16TSHRCHRM2CHRM4 | |
| SCHEMBL201963 | 0.84 | KDM4E (0.34) | — | |
| SCHEMBL6544577 | 0.83 | SLC22A16 (0.33) | MAPTSLC22A16 | |
| SCHEMBL347663 | 0.82 | KDM4E (0.38) | — | |
| SCHEMBL16553158 | 0.78 | KDM4E (0.35) | — | |
| SCHEMBL1133506 | 0.78 | USP2 (0.44) | TSHR | |
| SCHEMBL5958719 | 0.78 | HSD17B10 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163092-A | QUATERNIZED MONOMER, CROSS-LINKING AGENT | PLASTOMEDICAL SCIENCES, INC. (US) | 1979-07-31 | — | — | US | disclosed |