Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.31 |
| ▸ | ADRA1D known ✓ | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1B known ✓ | P35368 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2210061 | 0.89 | MAPT (0.34) | SMN1; SMN2SLC22A16MAPTTSHRCHRM2 | |
| Bromide SCHEMBL11520159 | 0.87 | MAPT (0.33) | SMN1; SMN2SLC22A16MAPTTSHRCHRM2 | |
| Hydrochloric Acid SCHEMBL204257 | 0.87 | MAPT (0.38) | SMN1; SMN2SLC22A16MAPTTSHRCHRM2 | |
| Sulfuric Acid SCHEMBL11519848 | 0.86 | SLC22A16 (0.36) | SMN1; SMN2SLC22A16MAPTTSHRCHRM2 | |
| SCHEMBL6544577 | 0.82 | SLC22A16 (0.33) | SLC22A16MAPT | |
| SCHEMBL201963 | 0.77 | KDM4E (0.34) | — | |
| SCHEMBL9175077 | 0.75 | LPAR5 (0.39) | LPAR5 | |
| SCHEMBL347663 | 0.75 | KDM4E (0.38) | — | |
| Phosphoric Acid SCHEMBL8763237 | 0.75 | TSHR (0.50) | SMN1; SMN2SLC22A16MAPTTSHRCHRM2 | |
| SCHEMBL7031787 | 0.74 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783589-A1 | TRANSPORTABILITY IMPROVER FOR PULVERIZED COAL | Kao Corporation (JP) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010093-A1 | TRANSPORTABILITY IMPROVER FOR PULVERIZED COAL | KAO CORPORATION (JP) | 1996-04-04 | — | — | WO | disclosed |