Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518080 | 0.89 | FFAR4 (0.56) | MAPTLMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL11521387 | 0.87 | MAPK1 (0.48) | MAPTLMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL11841874 | 0.80 | TDP1 (0.56) | MAPTLMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL10783122 | 0.78 | FFAR4 (0.53) | MAPTLMNAALDH1A1TDP1TSHR | |
| SCHEMBL5036438 | 0.77 | CA12 (0.51) | MAPTLMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL30060469 | 0.77 | MAPT (0.58) | MAPTLMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL7807114 | 0.77 | MAPT (0.58) | MAPTLMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL11490967 | 0.77 | KMT2A (0.56) | MAPTLMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL11663270 | 0.76 | TDP1 (0.54) | MAPTLMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL5033435 | 0.76 | ALDH1A1 (0.47) | MAPTLMNAALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176192-A | ANTHELMINTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-27 | — | — | US | disclosed |