Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11460518 | 0.86 | TDP1 (0.41) | TDP1GPR35ALDH1A1MAPTCHRNB2 | |
| SCHEMBL7785414 | 0.85 | ALDH1A1 (0.47) | TDP1GPR35ALDH1A1KMT2AMEN1 | |
| SCHEMBL27569119 | 0.85 | ERN1 (0.51) | TDP1ALDH1A1MAPTCHRNB2CHRNA4 | |
| SCHEMBL9099707 | 0.83 | KMT2A (0.48) | GPR35ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL28278687 | 0.83 | ALDH1A1 (0.46) | TDP1GPR35ALDH1A1KMT2AMEN1 | |
| SCHEMBL9099696 | 0.83 | KMT2A (0.48) | GPR35ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL1725391 | 0.81 | KMT2A (0.49) | TDP1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL14931287 | 0.81 | ALDH1A1 (0.45) | TDP1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL14931288 | 0.81 | ALDH1A1 (0.45) | TDP1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7335158 | 0.79 | HSP90AA1 (0.49) | TDP1ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150148-A | NITROSUBSTITUTED | WILLIAM H. RORER, INC. (US) | 1979-04-17 | — | — | US | claimed |