Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807633 | 0.84 | GAA (0.69) | GAATDP1ALDH1A1RXFP1POLB | |
| SCHEMBL11520930 | 0.79 | GAA (0.49) | GAATDP1ALDH1A1RXFP1POLB | |
| SCHEMBL11521033 | 0.79 | GAA (0.45) | GAATDP1ALDH1A1LMNA | |
| SCHEMBL11519609 | 0.78 | GAA (0.47) | GAATDP1ALDH1A1RXFP1POLB | |
| SCHEMBL11521372 | 0.77 | TDP1 (0.46) | GAATDP1ALDH1A1RXFP1POLB | |
| SCHEMBL11522501 | 0.75 | GAA (0.56) | GAATDP1ALDH1A1RXFP1POLB | |
| SCHEMBL11520610 | 0.74 | GAA (0.55) | GAATDP1ALDH1A1RXFP1POLB | |
| SCHEMBL11519108 | 0.74 | GAA (0.44) | GAATDP1ALDH1A1RXFP1POLB | |
| SCHEMBL11518156 | 0.73 | TDP1 (0.43) | GAATDP1ALDH1A1RXFP1POLB | |
| SCHEMBL11518677 | 0.73 | GAA (0.54) | GAATDP1ALDH1A1RXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152319-A | ALPHA, BETA-UNSATURATED AMIDES HAVING STERICALLY HINDERED PHENOLIC GROUP | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-05-01 | — | — | US | disclosed |