Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.41 |
| ▸ | ADH1B | P00325 | 2/20 | 0.41 |
| ▸ | ADH1C | P00326 | 2/20 | 0.41 |
| ▸ | ADH1A | P07327 | 2/20 | 0.41 |
| ▸ | ADH4 | P08319 | 2/20 | 0.41 |
| ▸ | ADH7 | P40394 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088379 | 0.98 | TSHR (0.52) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL11748886 | 0.96 | TSHR (0.46) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL24264956 | 0.91 | TSHR (0.44) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL1556475 | 0.91 | TSHR (0.46) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL11831004 | 0.91 | RELA (0.44) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL29940273 | 0.89 | TSHR (0.42) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL11555083 | 0.88 | ANPEP (0.45) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL11555809 | 0.88 | ANPEP (0.45) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL11551537 | 0.88 | ANPEP (0.45) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL11557215 | 0.88 | ANPEP (0.45) | TSHRALDH1A1ANPEPERAP2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179469-A | Preparation of amines | UOP INC. (US) | 1979-12-18 | — | — | US | disclosed |