Sugi Predict

Sugi Predict / Targets / RELA

RELA

Transcription factor p65 · Q04206 · RELA on Sugi Atlas →

361,439 patent compounds predicted against RELA, 233,857 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL59495 SCHEMBL59495 0.59 4/20
SCHEMBL12261 SCHEMBL12261 0.55 4/20
SCHEMBL60513 SCHEMBL60513 0.52 4/20
Ethylamine Ethylamine (SCHEMBL44330) 0.50 4/20
SCHEMBL36172 SCHEMBL36172 0.47 4/20
SCHEMBL62340 SCHEMBL62340 0.46 4/20
SCHEMBL56009 SCHEMBL56009 0.44 4/20
SCHEMBL9394 SCHEMBL9394 0.42 4/20
SCHEMBL22020 SCHEMBL22020 0.38 4/20
Biochanin Biochanin (SCHEMBL61258) 1.00 3/20
SCHEMBL52223 SCHEMBL52223 0.76 3/20
SCHEMBL52224 SCHEMBL52224 0.76 3/20
Echinocystic Acid Echinocystic Acid (SCHEMBL42864) 0.75 3/20
SCHEMBL59673 SCHEMBL59673 0.73 3/20
SCHEMBL60050 SCHEMBL60050 0.72 3/20
Ataluren Ataluren (SCHEMBL60614) 0.69 3/20
Ataluren Ataluren (SCHEMBL59165) 0.68 3/20
Ataluren Ataluren (SCHEMBL59167) 0.68 3/20
SCHEMBL23715 SCHEMBL23715 0.63 3/20
Ataluren Ataluren (SCHEMBL59166) 0.62 3/20

Clinical trials — most relevant to RELA by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Minocycline to Treat Childhood Regressive Autism PHASE4COMPLETED
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room PHASE2/PHASE3COMPLETED
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma PHASE1/PHASE2COMPLETED
Effects of Gum Arabic on Metabolic Syndrome Parameters in Postmenopausal Women PHASE2COMPLETED
Simvastatin in Secondary Progressive Multiple Sclerosis PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation PHASE2ACTIVE_NOT_RECRUITING
A Trial of Rosiglitazone for Ulcerative Colitis PHASE2COMPLETED
Denosumab for the Treatment of Adult LCH PHASE2COMPLETED
Tamoxifen and Bortezomib to Treat Recurrent Brain Tumors PHASE2COMPLETED
Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer Patients PHASE1/PHASE2COMPLETED
Chronic Obstructive Pulmonary Disease Transcription Factor and Cytokine Study EARLY_PHASE1COMPLETED
Card14gene (rs34367357 ) Polymorphism in Egyptian Psoriatic and Psoriatic Arthritis Patient nanRECRUITING
Novel Biomarkers in Inflammatory Bowel Disease nanCOMPLETED
Oxidative Stress in Intestinal Metaplasia and Metabolic Syndrome nanUNKNOWN
INTERVAL - Intense Exercise Trial for Men With Metastatic Castrate-Resistant Prostate Cancer nanUNKNOWN
Effect of Continuous Erector Spinae Plane Block With Ropivacaine on Postoperative Pain and NF-κB Levels After Mastectomy nanNOT_YET_RECRUITING
The Influence of Ventilation on Perioperative Neurocognitive Disorders nanWITHDRAWN
IKBKB Gene Polymorphism (Single Nucleotide Polymorphism) (SNP) in Psoriatic and Psoriatic Arthritis Patients nanCOMPLETED
Role of NFKBIA and PTPN22 Genes Polymorphism in Acute Rejection Susceptibility After Living Donor Liver Transplantation in Egyptian Patients. nanCOMPLETED
Diagnosis of Inflammatory Bowel Disease nanNOT_YET_RECRUITING
Optimal Treatment of Acute Skeletal Muscle Injury nanNOT_YET_RECRUITING
Preoperative Risk Factors and Perioperative Neurocognitive Disorders nanCOMPLETED
Evaluation of the Effect of Alpha Lipoic Acid on Radiation Induced Dermatitis in Breast Cancer Patients nanRECRUITING
MicroRNAs and Cytokines in Peri-Implantitis Tissue nanUNKNOWN
Mechanisms of Insulin Resistance in Humans nanCOMPLETED
Clinical Study Protocol for the Treatment of ND-AML and RR-AML With KMT2A Gene Abnormalities Using VHEA. nanRECRUITING
The Beneficial Effects of Pomegranate on Hearing of Patients Without Hemodialysis nanCOMPLETED
Role NLRP3 Inflammasome in Weight Loss Following Sleeve Gastrectomy in Morbidly Obese Patients nanUNKNOWN
Effects of Curcumin on Markers of Cardiovascular Risk in Patients With CAD nanWITHDRAWN

Related proteins — ESM-2 sequence neighbours (a RELA binder may also engage these)

ProteinNameSimilarity
Q04207 — 1.000 Q04207 →
Q7TQN4 — 1.000 Q7TQN4 →
P15307 — 0.982 P15307 →
P01126 — 0.981 P01126 →
P98152 — 0.980 P98152 →
Q04865 — 0.980 Q04865 →
P01125 — 0.980 P01125 →
P16236 — 0.980 P16236 →
Q62136 — 0.977 Q62136 →
P31266 — 0.973 P31266 →
REL Proto-oncogene c-Rel 0.973 landscape →
Q8BMI3 — 0.973 Q8BMI3 →
Q9CZT4 — 0.972 Q9CZT4 →
Q9NZ52 — 0.972 Q9NZ52 →
Q4VGL6 — 0.972 Q4VGL6 →
A0A0G2JV04 — 0.972 A0A0G2JV04 →
Q66IV1 — 0.971 Q66IV1 →
Q1L8L6 — 0.971 Q1L8L6 →
O54828 — 0.971 O54828 →
Q9UQB3 — 0.971 Q9UQB3 →
Q5M824 — 0.970 Q5M824 →
Q6NUC6 — 0.970 Q6NUC6 →
Q9NVU0 — 0.970 Q9NVU0 →
Q7Z5R6 — 0.970 Q7Z5R6 →
O35927 — 0.970 O35927 →
Q60596 — 0.970 Q60596 →
PTPN14 Tyrosine-protein phosphatase non-receptor type 14 0.969 landscape →
PTPN21 Protein-tyrosine phosphatase D1 0.969 landscape →
Q62925 — 0.969 Q62925 →
Q5PQS6 — 0.969 Q5PQS6 →