SCHEMBL11520586

SCHEMBL11520586

FC(Oc1c(F)c(F)c(F)c(F)c1F)=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.O=S(=O)(Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28979859 1.00 THRB (0.32) THRB
SCHEMBL29193597 0.91 THRB (0.33) THRB
SCHEMBL28357375 0.90
SCHEMBL29351674 0.89 THRB (0.32) THRB
Hydrochloric Acid SCHEMBL11522733 0.89 THRB (0.32) THRB
SCHEMBL11524073 0.89
SCHEMBL11523004 0.89
SCHEMBL30712104 0.89
SCHEMBL11519183 0.89
SCHEMBL28959126 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4163754-A Fluorinated sulfonamides ICI AMERICAS INC. (US) 1979-08-07 US claimed
US-4163754-A Fluorinated sulfonamides ICI AMERICAS INC. (US) 1979-08-07 US disclosed