Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520639 | 0.89 | ACHE (0.49) | TNFMAPTCRHBPCRHR2ACHE | |
| SCHEMBL10827267 | 0.81 | SRC (0.47) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11217486 | 0.80 | ACHE (0.56) | TNFMAPTCRHBPCRHR2ACHE | |
| SCHEMBL11520442 | 0.77 | IDO1 (0.48) | ALDH1A1SMN1; SMN2KMT2AGAAHPGD | |
| SCHEMBL11687914 | 0.76 | IDO1 (0.47) | MAPTKMT2A | |
| SCHEMBL5025148 | 0.73 | ACHE (0.63) | TNFACHETDP1L3MBTL1ALDH1A1 | |
| SCHEMBL5025140 | 0.72 | CYP2C19 (0.55) | ACHEL3MBTL1ALDH1A1LMNACA1 | |
| SCHEMBL8784523 | 0.71 | MAPT (0.69) | TNFMAPTCRHBPCRHR2ACHE | |
| SCHEMBL10917817 | 0.71 | IDO1 (0.48) | MAPTCRHBPCRHR2ALDH1A1LMNA | |
| SCHEMBL11464028 | 0.71 | SRC (0.54) | CRHBPCRHR2TDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |