SCHEMBL11520682

SCHEMBL11520682

COCC(=O)N(c1ccccc1Cl)C(C)C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
HTT P42858 2/20 0.40
PLA2G1B P04054 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 2/20 0.39
NOS3 P29474 2/20 0.37
NOS1 P29475 2/20 0.37
NOS2 P35228 2/20 0.37
RORC P51449 1/20 0.37
HPGD P15428 3/20 0.36
TSHR P16473 2/20 0.36
POLB P06746 2/20 0.35
BCL2A1 Q16548 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11518924 0.90 KMT2A (0.38) KMT2AMEN1HTTPLA2G1BNPSR1
SCHEMBL9505890 0.84 KMT2A (0.42) KMT2AMEN1HTTPLA2G1BNPSR1
SCHEMBL11521431 0.83 MEN1 (0.47) KMT2AMEN1HTTPLA2G1BNPSR1
SCHEMBL8622030 0.80 ALDH1A1 (0.46) KMT2AMEN1HTTPLA2G1BNPSR1
SCHEMBL8622032 0.80 ALDH1A1 (0.46) KMT2AMEN1HTTPLA2G1BNPSR1
Metalaxyl SCHEMBL9638624 0.77 KMT2A (0.55) KMT2AMEN1HTTPLA2G1BNPSR1
Metalaxyl SCHEMBL9638629 0.77 KMT2A (0.55) KMT2AMEN1HTTPLA2G1BNPSR1
Metalaxyl SCHEMBL20990 0.76 KMT2A (0.58) KMT2AMEN1HTTPLA2G1BNPSR1
Metalaxyl SCHEMBL8376541 0.76 KMT2A (0.58) KMT2AMEN1HTTPLA2G1BNPSR1
Mefenoxam SCHEMBL22529 0.76 KMT2A (0.58) KMT2AMEN1HTTPLA2G1BNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4151299-A Certain aniline derivatives as microbicidal agents CIBA-GEIGY CORPORATION (US) 1979-04-24 US claimed