Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14252255 | 0.86 | EGLN2 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1321345 | 0.86 | ALDH1A1 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30373299 | 0.86 | ALDH1A1 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL409948 | 0.86 | MEN1 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4314458 | 0.86 | NAMPT (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5961092 | 0.86 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL546514 | 0.86 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL289565 | 0.86 | LRRK2 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4778338 | 0.84 | CA12 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14797327 | 0.84 | NCEH1 (0.41) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159262-A | POLYIMIDES, POLYBENZIMIDAZOLES, POLYQUINOXALINES, POLYIMIDAZOPYRROLONES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR, NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1979-06-26 | — | — | US | disclosed |
| US-4061856-A | TO 1,3,5-TRIAZINES, SULFONIC, SULFINIC, PHOSPHONIC OR PHOSPHINIC ACID OR METAL ACETYLACETONATE CATALYST | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1977-12-06 | — | — | US | disclosed |