Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402681 | 0.74 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL10770872 | 0.72 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL10770869 | 0.72 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL10770339 | 0.71 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL10405233 | 0.70 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL11522382 | 0.69 | GAA (0.71) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL11521942 | 0.66 | KDM4E (0.30) | — | |
| SCHEMBL9332434 | 0.65 | — | — | |
| SCHEMBL7019206 | 0.65 | — | — | |
| SCHEMBL11143093 | 0.62 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1KMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |