Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.70 |
| ▸ | CA2 | P00918 | 7/20 | 0.70 |
| ▸ | CA12 | O43570 | 6/20 | 0.70 |
| ▸ | CA9 | Q16790 | 6/20 | 0.70 |
| ▸ | DRD4 | P21917 | 3/20 | 0.67 |
| ▸ | CA7 | P43166 | 2/20 | 0.67 |
| ▸ | CA4 | P22748 | 3/20 | 0.65 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679275 | 0.82 | DRD4 (0.79) | CA1CA2CA12CA9DRD4 | |
| SCHEMBL8740486 | 0.81 | DRD4 (1.00) | DRD4PPARGKMT2ADRD2DRD3 | |
| SCHEMBL579379 | 0.81 | CA1 (0.84) | CA1CA2CA12CA9CA4 | |
| SCHEMBL6961128 | 0.80 | DRD4 (0.77) | DRD4PPARGKMT2ADRD2DRD3 | |
| SCHEMBL9269749 | 0.80 | DRD4 (0.83) | DRD4PPARGKMT2ADRD2DRD3 | |
| SCHEMBL9269886 | 0.79 | DRD4 (0.80) | DRD4PPARGKMT2ADRD2DRD3 | |
| SCHEMBL9269193 | 0.79 | DRD4 (0.80) | DRD4PPARGKMT2ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL11130174 | 0.78 | DRD4 (0.79) | DRD4SCN8APPARGKMT2ADRD2 | |
| Benzenesulfonamide SCHEMBL29119602 | 0.78 | CA2 (0.86) | CA1CA2CA12CA9CA7 | |
| SCHEMBL10347029 | 0.77 | DRD4 (1.00) | DRD4PPARGKMT2ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137328-A | CONGESTIVE HEART FAILURE | PFIZER INC. (US) | 1979-01-30 | — | — | US | disclosed |