Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807148 | 0.79 | EPHX2 (0.59) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL23884204 | 0.76 | EPHX2 (0.61) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL27004562 | 0.75 | EPHX2 (0.59) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL13891367 | 0.75 | EPHX2 (0.59) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL8403724 | 0.75 | EPHX2 (0.66) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL4009926 | 0.75 | EPHX2 (0.59) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL1718112 | 0.75 | ALDH1A1 (0.73) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL5807144 | 0.75 | EPHX2 (0.59) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL11571847 | 0.73 | EPHX2 (0.59) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL31416867 | 0.73 | EPHX2 (0.57) | EPHX2EPHX1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138432-A | Amides of phosphonoacetic acid | ABBOTT LABORATORIES (US) | 1979-02-06 | — | — | US | disclosed |
| US-4087522-A | Amides of phosphonoacetic acid for treating herpes simplex virus type 1 and 2 infections | ABBOTT LABORATORIES (US) | 1978-05-02 | — | — | US | disclosed |