Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 4/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.45 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.43 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521627 | 1.00 | HSD17B1 (0.58) | HSD17B1ESR1ESR2HSD17B2ALDH1A1 | |
| SCHEMBL11525333 | 1.00 | HSD17B1 (0.58) | HSD17B1ESR1ESR2HSD17B2ALDH1A1 | |
| SCHEMBL11520044 | 0.89 | HSD17B1 (0.66) | HSD17B1ESR1ESR2HSD17B2ALDH1A1 | |
| SCHEMBL9755135 | 0.89 | HSD17B1 (0.70) | HSD17B1ESR1ESR2HSD17B2ALDH1A1 | |
| SCHEMBL11519678 | 0.84 | ESR1 (0.56) | HSD17B1ESR1ESR2HSD17B2ALDH1A1 | |
| SCHEMBL11522612 | 0.84 | ESR1 (0.56) | HSD17B1ESR1ESR2HSD17B2ALDH1A1 | |
| SCHEMBL11522635 | 0.82 | HSD17B1 (0.58) | HSD17B1ESR1ESR2HSD17B2PTP4A3 | |
| SCHEMBL11522025 | 0.82 | HSD17B1 (0.58) | HSD17B1ESR1ESR2HSD17B2PTP4A3 | |
| SCHEMBL11521308 | 0.82 | HSD17B1 (0.58) | HSD17B1ESR1ESR2HSD17B2ALDH1A1 | |
| SCHEMBL11521978 | 0.82 | HSD17B1 (0.58) | HSD17B1ESR1ESR2HSD17B2PTP4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | disclosed |