Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11927276 | 0.83 | GAA (0.73) | GAAL3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL1686848 | 0.83 | GAA (1.00) | GAAL3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL10402042 | 0.83 | GAA (0.73) | GAAL3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11522382 | 0.81 | GAA (0.71) | GAAL3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11802526 | 0.81 | GAA (0.71) | GAAL3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL14582756 | 0.79 | GAA (0.62) | GAAL3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL5038420 | 0.79 | ALDH1A1 (0.61) | GAARAB9ANPC1ALDH1A1POLB | |
| SCHEMBL11795775 | 0.79 | GAA (0.67) | GAAL3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11232213 | 0.78 | NPC1 (0.45) | GAAL3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL21303107 | 0.76 | GAA (0.62) | GAAL3MBTL1RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |