Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.79 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.68 |
| ▸ | OSBP | P22059 | 1/20 | 0.68 |
| ▸ | RORC | P51449 | 1/20 | 0.68 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.61 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.60 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.59 |
| ▸ | FNTA | P49354 | 1/20 | 0.58 |
| ▸ | FNTB | P49356 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.58 |
| ▸ | UGCG | Q16739 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25352571 | 1.00 | POLA1 (0.79) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL27319615 | 1.00 | POLA1 (0.79) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL3948833 | 1.00 | POLA1 (0.79) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL3948835 | 1.00 | POLA1 (0.79) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL3948836 | 0.96 | POLA1 (0.77) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL4123393 | 0.93 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL28673756 | 0.93 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL1621116 | 0.93 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL5329970 | 0.93 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL5329971 | 0.93 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175074-A | Serum-soluble cholesterol compounds and method for their preparation | MONOBIND, INC., A CORP. OF CA. | 1979-11-20 | — | — | US | disclosed |
| US-4070912-A | POLYMERIC MIXTURES OF A CHOLESTEROL AND A MONOMER | MCNAUGHTAN THOMAS J | 1978-01-31 | — | — | US | disclosed |
| US-4040784-A | Method for checking the accuracy of a test, using a serum-soluble cholesterol compound | MONOBIND, INC., A CORP. OF CA. | 1977-08-09 | — | — | US | disclosed |