Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.79 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.68 |
| ▸ | OSBP | P22059 | 1/20 | 0.68 |
| ▸ | RORC | P51449 | 1/20 | 0.68 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.61 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.60 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.59 |
| ▸ | FNTA | P49354 | 1/20 | 0.58 |
| ▸ | FNTB | P49356 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.58 |
| ▸ | GBA1 | P04062 | 1/20 | 0.58 |
| ▸ | UGCG | Q16739 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25352571 | 1.00 | POLA1 (0.79) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL27319615 | 1.00 | POLA1 (0.79) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL11522746 | 1.00 | POLA1 (0.79) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL3948833 | 1.00 | POLA1 (0.79) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL3948836 | 0.96 | POLA1 (0.77) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL4123393 | 0.93 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL28673756 | 0.93 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL1621116 | 0.93 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL5329970 | 0.93 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 | |
| SCHEMBL5329971 | 0.93 | POLA1 (0.73) | POLA1CYP46A1USP2LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670838-B1 | AMPHIPHILIC BLOCK COPOLYMER AND POLYMERIC COMPOSITION COMPRISING THE SAME FOR DRUG DELIVERY | SAMYANG BIOPHARMACEUTICALS (KR) | 2015-12-09 | — | — | EP | disclosed |
| US-8729257-B2 | Hybrid lipid compounds based on pentaerythritol, intermediates, preparation methods and use thereof | HARBIN INSTITUTE OF TECHNOLOGY (CN) | 2014-05-20 | — | — | US | disclosed |
| US-8349306-B2 | Hydrophilic comonomers of alkylene glycol, vinyl alcohols, vinylpyrrolidone, and/or acrylamide; hydrophobic comonoomer of lactic acid, glycolic acid, 6-hydroxycaproic acid, and/or dioxan-2-one substituted with tocopherol or cholesterol; stable micelles for delivery of anticarcinogenic agents | SAMYANG BIOPHARMACEUTICALS CORPORATION (KR) | 2013-01-08 | — | — | US | disclosed |
| US-20120116064-A1 | HYBRID LIPID COMPOUNDS BASED ON PENTAERYTHRITOL, INTERMEDIATES, PREPARATION METHODS AND USE THEREOF | HARBIN INSTITUTE OF TECHNOLOGY (CN) | 2012-05-10 | — | — | US | disclosed |
| EP-1670838-A4 | AMPHIPHILIC BLOCK COPOLYMER AND POLYMERIC COMPOSITION COMPRISING THE SAME FOR DRUG DELIVERY | SAMYANG CORP (KR) | 2009-07-08 | — | — | EP | disclosed |
| CN-100471886-C | Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery | SAMYANG CORP (KR) | 2009-03-25 | — | — | CN | disclosed |
| US-20080152616-A1 | Amphiphilic block copolymer and polymeric compostition comprising the same for drug delivery | SAMYANG HOLDINGS CORPORATION (KR) | 2008-06-26 | — | — | US | disclosed |
| US-7311901-B2 | Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery | SAMYANG CORPORATION (KR) | 2007-12-25 | — | — | US | disclosed |
| EP-1670838-A1 | AMPHIPHILIC BLOCK COPOLYMER AND POLYMERIC COMPOSITION COMPRISING THE SAME FOR DRUG DELIVERY | Samyang Corporation (KR) | 2006-06-21 | — | — | EP | disclosed |
| CN-1780865-A | Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery | SAMYANG CORP (KR) | 2006-05-31 | — | — | CN | disclosed |
| US-20050201972-A1 | Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery | SAMYANG CORPORATION | 2005-09-15 | — | — | US | disclosed |
| WO-2005035606-A1 | AMPHIPHILIC BLOCK COPOLYMER AND POLYMERIC COMPOSITION COMPRISING THE SAME FOR DRUG DELIVERY | SAMYANG CORPORATION (KR) | 2005-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080152616-A1 | Amphiphilic block copolymer and polymeric compostition comprising the same for drug delivery | CETP, ABCB4, TPRKB | POLA1 2142/4885CYP46A1 22/4885USP2 1543/4885 |
| US-20120116064-A1 | HYBRID LIPID COMPOUNDS BASED ON PENTAERYTHRITOL, INTERMEDIATES, PREPARATION METHODS AND USE THEREOF | CETP, NPC1L1, ABCB4 | POLA1 3977/4885CYP46A1 18/4885USP2 439/4885 |
| US-20050201972-A1 | Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery | TTPA, CETP, CHKB | POLA1 2927/4885CYP46A1 110/4885USP2 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.