Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1D | Q01668 | 10/20 | 0.64 |
| ▸ | CACNA1F | O60840 | 9/20 | 0.64 |
| ▸ | CACNA1S | Q13698 | 9/20 | 0.64 |
| ▸ | CACNA1C | Q13936 | 9/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11775245 | 0.88 | CACNA1D (0.64) | CACNA1DCACNA1FCACNA1SCACNA1CLMNA | |
| SCHEMBL9734505 | 0.86 | CACNA1F (0.57) | CACNA1DCACNA1FCACNA1SCACNA1CLMNA | |
| SCHEMBL11526085 | 0.84 | ABCC1 (0.61) | CACNA1DCACNA1FCACNA1SCACNA1CLMNA | |
| SCHEMBL9849848 | 0.84 | ADORA3 (0.62) | CACNA1DCACNA1FCACNA1SCACNA1CLMNA | |
| SCHEMBL11774771 | 0.84 | CACNA1D (0.58) | CACNA1DCACNA1FCACNA1SCACNA1CLMNA | |
| SCHEMBL10684386 | 0.83 | ADORA3 (0.75) | CACNA1DCACNA1FCACNA1SCACNA1CLMNA | |
| SCHEMBL11470832 | 0.83 | CACNA1D (0.59) | CACNA1DCACNA1FCACNA1SCACNA1CLMNA | |
| SCHEMBL24625058 | 0.83 | CACNA1D (0.58) | CACNA1DCACNA1FCACNA1SCACNA1CLMNA | |
| SCHEMBL7586726 | 0.82 | CACNA1C (0.60) | CACNA1DCACNA1FCACNA1SCACNA1CLMNA | |
| SCHEMBL14616736 | 0.81 | ADORA3 (0.85) | CACNA1DCACNA1FCACNA1SCACNA1CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146627-A | AMINOALKYLIDEAMINO-1,4-DIHYDROPYRIDINES AND THEIR USE AS MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |