Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARG | Q86W56 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4122753 | 0.83 | AKR1C3 (0.64) | ERN1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL31652668 | 0.83 | AKR1C3 (0.64) | ERN1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| Hydrochloric Acid SCHEMBL11522996 | 0.82 | AKR1C3 (0.62) | ERN1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL221422 | 0.82 | MAOA (0.49) | ERN1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11760933 | 0.81 | AKR1C4 (0.67) | ERN1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL30855203 | 0.79 | ERN1 (0.46) | ERN1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL21046886 | 0.79 | ERN1 (0.46) | ERN1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29334185 | 0.79 | ERN1 (0.46) | ERN1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29683224 | 0.79 | ERN1 (0.46) | ERN1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL4891035 | 0.78 | AKR1C4 (0.69) | ERN1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159342-A | Substituted 2-acyloxybenzoic acid anilides | BAYER AKTIENGESELLSCHAFT (DE) | 1979-06-26 | — | — | US | disclosed |