Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330408 | 0.83 | KCNA3 (0.58) | KCNA3TAAR1ALDH1A1RECQLLTA4H | |
| SCHEMBL4048803 | 0.79 | KCNA3 (0.54) | KCNA3TAAR1ALDH1A1RECQLLTA4H | |
| SCHEMBL6698794 | 0.79 | KCNA3 (0.54) | KCNA3TAAR1ALDH1A1RECQLSCN4A | |
| SCHEMBL4286719 | 0.79 | SCN4A (0.68) | KCNA3TAAR1ALDH1A1RECQLSCN4A | |
| SCHEMBL10784029 | 0.79 | KCNA3 (0.54) | KCNA3TAAR1ALDH1A1RECQLSCN4A | |
| SCHEMBL749890 | 0.79 | KCNA3 (0.54) | KCNA3TAAR1ALDH1A1RECQLLTA4H | |
| SCHEMBL321110 | 0.79 | KCNA3 (0.54) | KCNA3TAAR1ALDH1A1RECQLSCN4A | |
| SCHEMBL11217283 | 0.78 | KCNA3 (0.52) | KCNA3TAAR1ALDH1A1RECQLSCN4A | |
| SCHEMBL1017942 | 0.78 | KCNA3 (0.52) | KCNA3TAAR1ALDH1A1RECQLLTA4H | |
| SCHEMBL5681300 | 0.76 | LTA4H (0.50) | KCNA3TAAR1ALDH1A1RECQLSCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179500-A | 1,4-Dihydropyridine-sugar derivatives, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | claimed |