Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 5/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 3/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527129 | 0.93 | HRH2 (0.34) | HRH2HRH4HRH3F10XDH | |
| SCHEMBL11524943 | 0.93 | QPCT (0.31) | — | |
| SCHEMBL11522698 | 0.91 | XDH (0.36) | HRH2HRH4HRH3XDHHRH1 | |
| SCHEMBL11524957 | 0.90 | XDH (0.36) | HRH2HRH4HRH3XDH | |
| SCHEMBL11525284 | 0.89 | XDH (0.36) | HRH2XDH | |
| SCHEMBL11523503 | 0.89 | XDH (0.36) | HRH2XDH | |
| SCHEMBL11526556 | 0.89 | XDH (0.36) | HRH2XDH | |
| SCHEMBL11526828 | 0.85 | XDH (0.32) | XDH | |
| SCHEMBL11526991 | 0.85 | HRH4 (0.46) | HRH2HRH4HRH3HRH1 | |
| SCHEMBL11522481 | 0.85 | GABRR1 (0.32) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166860-A | TREATMENT OF ACHLORHYDRIA AND DYSMENORRHEA | WILLIAM H. RORER, INC. (US) | 1979-09-04 | — | — | US | disclosed |