Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.65 |
| ▸ | PPARA | Q07869 | 3/20 | 0.65 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.46 |
| ▸ | SLC8A1 | P32418 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2133112 | 0.89 | PPARG (0.65) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL7296313 | 0.83 | PPARG (0.51) | PPARGPPARACYP4F2CYP4A11NFKB1 | |
| SCHEMBL7296319 | 0.83 | PPARG (0.51) | PPARGPPARACYP4F2CYP4A11NFKB1 | |
| SCHEMBL11527877 | 0.82 | PPARG (0.52) | PPARGPPARAPPARDSLC8A1FAAH | |
| SCHEMBL9254934 | 0.82 | PPARG (0.53) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL7079479 | 0.81 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL7085487 | 0.81 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL29587603 | 0.79 | HDAC3 (0.49) | PPARGPPARACYP4F2CYP4A11FAAH | |
| SCHEMBL11526092 | 0.79 | HDAC3 (0.49) | PPARGPPARACYP4F2CYP4A11FAAH | |
| SCHEMBL29388635 | 0.78 | HPGD (0.49) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178380-A | LIPOGENSIS INHIBITORS | SHELL OIL COMPANY (US) | 1979-12-11 | — | — | US | disclosed |