Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296319 | 0.87 | PPARG (0.51) | PPARGPPARACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL7296313 | 0.87 | PPARG (0.51) | PPARGPPARACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL11523391 | 0.82 | PPARG (0.65) | PPARGPPARACYP4F2CYP4A11PPARD | |
| SCHEMBL433940 | 0.80 | CYP4F2 (0.50) | PPARGPPARACYP4F2CYP4A11CYSLTR1 | |
| SCHEMBL7567839 | 0.80 | CA2 (0.44) | CYP4F2CYP4A11CA2CA5AALDH1A1 | |
| SCHEMBL4193774 | 0.78 | ESR1 (0.56) | PPARGPPARACYP4F2CYP4A11NFKB1 | |
| SCHEMBL7290410 | 0.78 | ESR1 (0.56) | PPARGPPARACYP4F2CYP4A11NFKB1 | |
| SCHEMBL5847422 | 0.77 | CYP2D6 (0.52) | CYP4F2CYP4A11MAPTSMN1; SMN2NFKB1 | |
| SCHEMBL5847418 | 0.77 | CYP2D6 (0.52) | CYP4F2CYP4A11MAPTSMN1; SMN2NFKB1 | |
| SCHEMBL5847426 | 0.77 | CYP2D6 (0.52) | CYP4F2CYP4A11MAPTSMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |