Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523393 | 1.00 | GRIA1 (0.44) | GRIA1GRIA2GRIA3USP30GRM2 | |
| SCHEMBL11527214 | 0.99 | GRIA1 (0.44) | GRIA1GRIA2GRIA3USP30GRM2 | |
| SCHEMBL11527218 | 0.99 | GRIA1 (0.44) | GRIA1GRIA2GRIA3USP30GRM2 | |
| SCHEMBL11525277 | 0.96 | GRIA1 (0.45) | GRIA1GRIA2GRIA3USP30GRM2 | |
| SCHEMBL11525272 | 0.96 | GRIA1 (0.45) | GRIA1GRIA2GRIA3USP30GRM2 | |
| SCHEMBL11524748 | 0.90 | GRIA2 (0.47) | GRIA1GRIA2GRIA3USP30TSHR | |
| SCHEMBL11524743 | 0.90 | GRIA2 (0.47) | GRIA1GRIA2GRIA3USP30TSHR | |
| SCHEMBL24471099 | 0.89 | GRIA2 (0.50) | GRIA1GRIA2GRIA3USP30GRIA4 | |
| SCHEMBL19464663 | 0.85 | TSHR (0.50) | GRIA1GRIA2GRIA3GRM2TSHR | |
| SCHEMBL11617404 | 0.85 | SPHK1 (0.41) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |