Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 3/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524743 | 1.00 | GRIA2 (0.47) | GRIA2GRIA1GRIA3USP30GRIA4 | |
| SCHEMBL24471099 | 0.92 | GRIA2 (0.50) | GRIA2GRIA1GRIA3USP30GRIA4 | |
| SCHEMBL11525272 | 0.92 | GRIA1 (0.45) | GRIA2GRIA1GRIA3USP30GRIA4 | |
| SCHEMBL11525277 | 0.92 | GRIA1 (0.45) | GRIA2GRIA1GRIA3USP30GRIA4 | |
| SCHEMBL11523393 | 0.90 | GRIA1 (0.44) | GRIA2GRIA1GRIA3USP30GRIA4 | |
| SCHEMBL11523399 | 0.90 | GRIA1 (0.44) | GRIA2GRIA1GRIA3USP30GRIA4 | |
| SCHEMBL11527214 | 0.89 | GRIA1 (0.44) | GRIA2GRIA1GRIA3USP30TSHR | |
| SCHEMBL11527218 | 0.89 | GRIA1 (0.44) | GRIA2GRIA1GRIA3USP30TSHR | |
| SCHEMBL11527145 | 0.88 | GRIA1 (0.49) | GRIA2GRIA1GRIA3USP30GRIA4 | |
| SCHEMBL11527149 | 0.88 | GRIA1 (0.49) | GRIA2GRIA1GRIA3USP30GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |