Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949519 | 0.84 | HCAR2 (0.53) | HCAR2ATMPLA2G1BATG4BACHE | |
| SCHEMBL7949527 | 0.84 | HCAR2 (0.53) | HCAR2ATMPLA2G1BATG4BACHE | |
| SCHEMBL10837365 | 0.81 | HCAR2 (0.50) | HCAR2ATMPLA2G1BATG4BACHE | |
| SCHEMBL8467697 | 0.79 | HCAR2 (0.51) | HCAR2ATMPLA2G1BATG4BACHE | |
| SCHEMBL28345184 | 0.79 | TSHR (0.48) | ATM | |
| SCHEMBL29041003 | 0.78 | HCAR2 (0.56) | HCAR2ATMPLA2G1BATG4B | |
| SCHEMBL10426087 | 0.77 | HCAR2 (0.50) | HCAR2ATMACHEBACE1 | |
| SCHEMBL10396415 | 0.77 | HCAR2 (0.50) | HCAR2ATMACHEBACE1 | |
| SCHEMBL11749694 | 0.77 | HCAR2 (0.50) | HCAR2ATM | |
| SCHEMBL9328096 | 0.77 | HCAR2 (0.50) | HCAR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153640-A | POLYALKYLHYDROGENSILOXANE, HYDROXYALKYL ACRYLATE | CIBA-GEIGY CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |