SCHEMBL8467697

SCHEMBL8467697

CCCCC(I)(I)OC(=O)C=CC(=O)O

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.51
ATM Q13315 1/20 0.40
PLA2G1B P04054 5/20 0.33
ATG4B Q9Y4P1 5/20 0.33
ACHE P22303 1/20 0.33
BACE1 P56817 1/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
CYP1A2 P05177 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7949527 0.81 HCAR2 (0.53) HCAR2ATMPLA2G1BATG4BACHE
SCHEMBL7949519 0.81 HCAR2 (0.53) HCAR2ATMPLA2G1BATG4BACHE
SCHEMBL11523645 0.79 HCAR2 (0.51) HCAR2ATMPLA2G1BATG4BACHE
SCHEMBL10837365 0.78 HCAR2 (0.50) HCAR2ATMPLA2G1BATG4BACHE
SCHEMBL7502212 0.76 HCAR2 (0.57) HCAR2ATMPLA2G1BATG4BTHRA
SCHEMBL7502219 0.76 HCAR2 (0.57) HCAR2ATMPLA2G1BATG4BTHRA
SCHEMBL1301122 0.75 HCAR2 (0.53) HCAR2ATMPLA2G1BATG4BTHRA
SCHEMBL128174 0.75 HCAR2 (0.53) HCAR2ATMPLA2G1BATG4BTHRA
SCHEMBL10673266 0.75 HCAR2 (0.53) HCAR2ATMPLA2G1BATG4BTHRA
SCHEMBL29041003 0.75 HCAR2 (0.56) HCAR2ATMPLA2G1BATG4BTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5912301-A SUSPENSION OF POLYOLEFIN AND UNSATURATED GLYCIDYL ESTER, VINYL MONOMER WITH FREE RADICAL INITIATOR FOR MOLDABILITY KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-06-15 US disclosed
EP-0811643-A1 GRAFTED POLYOLEFINIC RESIN AND COMPOSITION THEREOF KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-12-10 EP disclosed
EP-0779307-A1 GRAFT ETHYLENE-VINYL ACETATE COPOLYMER AND RESIN COMPOSITION CONTAINING THE SAME KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-06-18 EP disclosed
EP-0656376-A1 Graft-modified polyolefin resin composition and thermoplastic resin composition containing the same KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1995-06-07 EP disclosed