Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GRK2 | P25098 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525130 | 0.91 | POLB (0.51) | POLBGRK2DNMT1CTDSP1MAPT | |
| SCHEMBL14079408 | 0.85 | POLB (0.43) | POLBGRK2DNMT1CTDSP1MAPT | |
| SCHEMBL9818478 | 0.83 | MAPT (0.48) | POLBGRK2DNMT1CTDSP1MAPT | |
| SCHEMBL11739547 | 0.80 | POLB (0.52) | POLBGRK2DNMT1CTDSP1MAPT | |
| SCHEMBL14079442 | 0.78 | MAPT (0.52) | POLBGRK2DNMT1CTDSP1MAPT | |
| SCHEMBL14079444 | 0.76 | HTT (0.51) | POLBGRK2DNMT1CTDSP1MAPT | |
| SCHEMBL13650233 | 0.75 | MAPT (0.51) | POLBGRK2DNMT1CTDSP1MAPT | |
| SCHEMBL14079413 | 0.75 | POLB (0.48) | POLBGRK2DNMT1CTDSP1MAPT | |
| SCHEMBL14079411 | 0.75 | MAPT (0.49) | POLBGRK2DNMT1CTDSP1MAPT | |
| SCHEMBL8597482 | 0.75 | MAPT (0.48) | POLBGRK2DNMT1CTDSP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157915-A | (2-BENZENESULFONYL)-ETHOXYCARBONYLAMINO-ANILINE COMPOUND AS THE PRECURSOR | FUJI PHOTO FILM CO., LTD. (JP) | 1979-06-12 | — | — | US | disclosed |