SCHEMBL9818478

SCHEMBL9818478

CCN(CCNS(C)(=O)=O)c1ccc(NC(=O)Oc2ccccc2)c(C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 13/20 0.48
HTT P42858 4/20 0.48
LMNA P02545 4/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
HSD17B10 Q99714 2/20 0.48
GFER P55789 6/20 0.44
KMT2A Q03164 5/20 0.44
MAPK1 P28482 4/20 0.44
ALDH1A1 P00352 4/20 0.44
MEN1 O00255 4/20 0.44
ALOX15 P16050 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
POLB P06746 1/20 0.43
GRK2 P25098 1/20 0.43
DNMT1 P26358 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
CYP2C19 P33261 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13650229 0.86 MAPT (0.61) MAPTHTTLMNASMN1; SMN2HSD17B10
SCHEMBL11523698 0.83 POLB (0.50) MAPTHTTLMNASMN1; SMN2HSD17B10
SCHEMBL11739547 0.83 POLB (0.52) MAPTHTTLMNASMN1; SMN2HSD17B10
SCHEMBL8597482 0.79 MAPT (0.48) MAPTHTTLMNASMN1; SMN2HSD17B10
SCHEMBL14079408 0.79 POLB (0.43) MAPTHTTLMNASMN1; SMN2HSD17B10
SCHEMBL9453024 0.78 RPS6KA2 (0.45) MAPTHTTLMNASMN1; SMN2GFER
SCHEMBL9633385 0.78 POLB (0.42) MAPTHTTLMNASMN1; SMN2HSD17B10
SCHEMBL11525252 0.78 MAPT (0.41) MAPTHTTLMNASMN1; SMN2HSD17B10
SCHEMBL13650231 0.77 MAPT (0.45) MAPTHTTLMNASMN1; SMN2HSD17B10
SCHEMBL11525130 0.76 POLB (0.51) MAPTHTTLMNASMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5002862-A Method for processing a silver halide color photographic material with a color developer comprising an aromatic primary amine precursor FUJI PHOTO FILM CO. (JP) 1991-03-26 US disclosed
US-4157915-A (2-BENZENESULFONYL)-ETHOXYCARBONYLAMINO-ANILINE COMPOUND AS THE PRECURSOR FUJI PHOTO FILM CO., LTD. (JP) 1979-06-12 US disclosed