Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.41 |
| ▸ | PNMT | P11086 | 6/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11592050 | 0.81 | GRIN2B (0.41) | GRIN2BPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL8765980 | 0.80 | GRIN2B (0.41) | GRIN2BPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL8765757 | 0.79 | GRIN2B (0.63) | GRIN2BALDH1A1MAPTCRHBPCRHR2 | |
| SCHEMBL12670596 | 0.73 | GRIN2B (0.61) | GRIN2BPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL11591650 | 0.71 | GRIN2B (0.40) | GRIN2BPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL3442079 | 0.70 | CA9 (0.47) | GRIN2BPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL23195867 | 0.69 | PNMT (0.42) | GRIN2BPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL23195881 | 0.69 | PNMT (0.42) | GRIN2BPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL8766380 | 0.68 | CA9 (0.44) | GRIN2BPNMTADRA2AADRA2BADRA2C | |
| SCHEMBL7208524 | 0.67 | PNMT (0.53) | PNMTADRA2AADRA2BADRA2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154852-A | ANTIDEPRESSANTS | ROUSSEL UCLAF (FR) | 1979-05-15 | — | — | US | disclosed |