Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4493049 | 0.86 | IDO1 (0.41) | HTR2CHTR2AHTR2B | |
| SCHEMBL4485116 | 0.86 | IDO1 (0.41) | HTR2CHTR2AHTR2B | |
| SCHEMBL13627349 | 0.86 | IDO1 (0.41) | HTR2CHTR2AHTR2B | |
| SCHEMBL4478604 | 0.86 | IDO1 (0.41) | HTR2CHTR2AHTR2B | |
| SCHEMBL13627351 | 0.86 | IDO1 (0.41) | HTR2CHTR2AHTR2B | |
| SCHEMBL13627350 | 0.86 | IDO1 (0.41) | HTR2CHTR2AHTR2B | |
| SCHEMBL13637322 | 0.86 | IDO1 (0.41) | HTR2CHTR2AHTR2B | |
| SCHEMBL4241281 | 0.86 | IDO1 (0.41) | HTR2CHTR2AHTR2B | |
| SCHEMBL11412368 | 0.86 | CHRNB4 (0.46) | HTR2CHTR2AHTR2BHTR5ACHRNB4 | |
| SCHEMBL11505432 | 0.78 | HTR2A (0.44) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177275-A | Tension reducing 2,3,4,4a,9,13b-hexahydro-1H-dibenzo[b,f]pyrido[3,4-d]azepine derivatives | AKZONA INC. (US) | 1979-12-04 | — | — | US | disclosed |