SCHEMBL11523935

SCHEMBL11523935

CCCCOC(=O)C(=Cc1ccc(O)cc1)C(=O)OCCCC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.55
LMNA P02545 3/20 0.55
TSHR P16473 3/20 0.55
CYP1A2 P05177 2/20 0.55
MAPK1 P28482 2/20 0.55
CYP2C19 P33261 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
CYP2D6 P10635 1/20 0.55
NR1H2 P55055 1/20 0.55
RNASEL Q05823 1/20 0.55
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
MAPT P10636 3/20 0.53
NPSR1 Q6W5P4 2/20 0.53
CYP2C9 P11712 1/20 0.53
S1PR4 O95977 1/20 0.53
S1PR1 P21453 1/20 0.53
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 2/20 0.50
NR1H4 Q96RI1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11800607 0.94 LMNA (0.50) ESR1LMNATSHRCYP1A2MAPK1
SCHEMBL12869950 0.90 MEN1 (0.56) ESR1LMNATSHRCYP1A2MAPK1
SCHEMBL15673155 0.87 KMT2A (0.70) LMNATSHRCYP1A2MAPK1CYP2C19
SCHEMBL28841141 0.86 KMT2A (0.51) LMNATSHRCYP1A2MAPK1CYP2C19
SCHEMBL5607649 0.86 ESR1 (0.54) ESR1LMNATSHRCYP1A2MAPK1
SCHEMBL5607541 0.86 ESR1 (0.54) ESR1LMNATSHRCYP1A2MAPK1
SCHEMBL5607536 0.86 ESR1 (0.54) ESR1LMNATSHRCYP1A2MAPK1
SCHEMBL5606755 0.85 ESR1 (0.53) ESR1LMNATSHRCYP1A2MAPK1
SCHEMBL5606821 0.84 ESR1 (0.51) ESR1LMNATSHRCYP1A2MAPK1
SCHEMBL5607647 0.84 ESR1 (0.51) ESR1LMNATSHRCYP1A2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4158658-A Bichromophoric benzoxazole-styrene ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1979-06-19 US disclosed
US-4075162-A BICHROMOPHORIC BENZOXAZOLE-STYRENE ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed