SCHEMBL11524375

SCHEMBL11524375

O=C(Cl)c1ccc(-c2nc(-c3ccccc3)co2)cc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMO Q99835 2/20 0.57
ENPP3 O14638 3/20 0.55
ENPP1 P22413 2/20 0.55
HSD17B1 P14061 1/20 0.49
HSD17B2 P37059 1/20 0.49
ALDH1A1 P00352 1/20 0.49
HDAC6 Q9UBN7 4/20 0.48
HDAC1 Q13547 3/20 0.48
HDAC8 Q9BY41 3/20 0.48
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
PDE4B Q07343 1/20 0.41
CTRC Q99895 1/20 0.40
DAGLA Q9Y4D2 1/20 0.40
HSD11B1 P28845 1/20 0.40
KDM4E B2RXH2 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7215644 0.88 NPC1 (0.58) SMOENPP3ENPP1HSD17B1HSD17B2
SCHEMBL7215456 0.88 NPC1 (0.58) SMOENPP3ENPP1HSD17B1HSD17B2
SCHEMBL3271684 0.83 ENPP3 (0.72) SMOENPP3ENPP1HSD17B1HSD17B2
SCHEMBL11566150 0.83 ENPP3 (0.72) SMOENPP3ENPP1HSD17B1HSD17B2
SCHEMBL5664564 0.82 ENPP3 (0.75) SMOENPP3ENPP1HSD17B1HSD17B2
SCHEMBL278182 0.82 ENPP3 (0.69) SMOENPP3ENPP1HSD17B1HSD17B2
Benzene SCHEMBL16781371 0.82 ENPP3 (0.69) SMOENPP3ENPP1HSD17B1HSD17B2
SCHEMBL7221412 0.81 ENPP3 (0.62) SMOENPP3ENPP1HSD17B1HSD17B2
SCHEMBL31606598 0.80 ENPP3 (0.67) SMOENPP3ENPP1HSD17B1HSD17B2
SCHEMBL28474694 0.79 ENPP3 (0.62) SMOENPP3ENPP1HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4159985-A Heterocyclic phenyl ester ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-07-03 US disclosed
US-4140674-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1979-02-20 US disclosed
US-4020080-A Oxadiazolylphenyl aromatic ester compounds and their use as ultraviolet stabilizer in organic compositions EASTMAN KODAK COMPANY (US) 1977-04-26 US disclosed