Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11406174 | 0.95 | KDM4E (0.55) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL11524047 | 0.93 | KDM4E (0.53) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL11524205 | 0.92 | ALDH1A1 (0.52) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11520770 | 0.88 | ALDH1A1 (0.50) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL621847 | 0.87 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTHPGDALOX15 | |
| SCHEMBL11523483 | 0.87 | POLB (0.54) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL11803186 | 0.87 | ALDH1A1 (0.49) | KDM4EALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL9621940 | 0.86 | HDAC3 (0.59) | KDM4EALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL9621938 | 0.86 | HDAC3 (0.59) | KDM4EALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL9621976 | 0.86 | HDAC3 (0.59) | KDM4EALDH1A1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139528-A | Water-insoluble monoazo dyestuffs which is a diazotized 6-cyano-2:4-dinitroaniline coupled to a m-acylamino-substituted aniline | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-02-13 | — | — | US | disclosed |