SCHEMBL1152456

SCHEMBL1152456

CC(NC(=O)O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18125953 1.00
SCHEMBL1152458 1.00
SCHEMBL21202140 0.81 SMN1; SMN2 (0.47)
SCHEMBL10403225 0.81
SCHEMBL18180339 0.81 SMN1; SMN2 (0.47)
SCHEMBL330308 0.79
SCHEMBL330009 0.79
SCHEMBL330011 0.79
SCHEMBL15740599 0.79
SCHEMBL1696899 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110045514-A1 METHODS FOR DETECTING MAJOR ADVERSE CARDIOVASCULAR AND CEREBROVASCULAR EVENTS BG MEDICINE, INC. (US) 2011-02-24 US claimed
EP-2210108-A2 METHODS FOR DETECTING MAJOR ADVERSE CARDIOVASCULAR AND CEREBROVASCULAR EVENTS BG Medicine, Inc. (US) 2010-07-28 EP claimed
WO-2009049189-A2 METHODS FOR DETECTING MAJOR ADVERSE CARDIOVASCULAR AND CEREBROVASCULAR EVENTS BG MEDICINE, INC. (US) 2009-04-16 WO claimed
US-20230338257-A1 ANHYDROUS CONCENTRATED HAIR CARE COMPOSITIONS IN THE FORM OF A PASTE EVERIST INC. (CA) 2023-10-26 US disclosed
EP-3253752-B1 [9,10-DIMETHOXY-3-(2-METHYLPROPYL)-1H,2H,3H,4H,6H,7H,11BH-PYRIDO-[2,1-A]ISOQUINOLIN-2-YL]METHANOL AND COMPOUNDS, COMPOSITIONS AND METHODS RELATING THERETO NEUROCRINE BIOSCIENCES INC (US) 2023-08-16 EP disclosed
CN-107922371-B N-substituted hydroxamic acids with carbon-based leaving groups as efficient HNO donors and uses thereof 约翰斯霍普金斯大学 2022-04-19 CN disclosed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
CN-112912002-A Improved light transmissive sample holder and analysis, particularly for hemoglobin ESSENLIX公司 2021-06-04 CN disclosed
US-9670473-B2 Crystals of angiotensin-converting enzyme (ACE) ANGIODESIGN (UK) LIMITED (GB) 2017-06-06 US disclosed
CN-104321356-B Comprise water solublity N-(2 hydroxyalkyl) (methyl) acrylamide polymer or the adherent lens of copolymer 庄臣及庄臣视力保护公司 2016-12-28 CN disclosed
US-20160333334-A1 CRYSTAL UNIVERSITY OF BATH (GB) 2016-11-17 US disclosed
EP-2210108-A2 METHODS FOR DETECTING MAJOR ADVERSE CARDIOVASCULAR AND CEREBROVASCULAR EVENTS BG Medicine, Inc. (US) 2010-07-28 EP disclosed
US-20100173977-A1 Crystal UNIVERSITY OF BATH (GB) 2010-07-08 US disclosed
WO-2009049189-A2 METHODS FOR DETECTING MAJOR ADVERSE CARDIOVASCULAR AND CEREBROVASCULAR EVENTS BG MEDICINE, INC. (US) 2009-04-16 WO disclosed
EP-1984008-A2 ACE N-DOMAIN CRYSTAL University of Cape Town (ZA) 2008-10-29 EP disclosed
WO-2007080400-A2 ACE N-DOMAIN CRYSTAL UNIVERSITY OF CAPE TOWN (ZA) 2007-07-19 WO disclosed
US-4914206-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-04-03 US disclosed
EP-0019225-B1 PROCESS FOR THE PREPARATION OF N-VINYL-N-ALKYL CARBOXYLIC ACID AMIDES HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-24 EP disclosed
EP-0030609-A1 Process for the preparation of N-alpha-alkoxyalkyl carboxylic acid amides, some representatives of these compounds, and their ensuing products HOECHST AKTIENGESELLSCHAFT (DE) 1981-06-24 EP disclosed
US-4115306-A WATER RESISTANCE THROUGH CURING CHAS. S. TANNER CO. (US) 1978-09-19 US disclosed