SCHEMBL1152458

SCHEMBL1152458

C[C@H](NC(=O)O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1152456 1.00
SCHEMBL18125953 1.00
SCHEMBL21202140 0.81 SMN1; SMN2 (0.47)
SCHEMBL10403225 0.81
SCHEMBL18180339 0.81 SMN1; SMN2 (0.47)
SCHEMBL330308 0.79
SCHEMBL330009 0.79
SCHEMBL330011 0.79
SCHEMBL15740599 0.79
SCHEMBL1696899 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210138117-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2021-05-13 US claimed
US-10874766-B2 Compounds and matrices for use in bone growth and repair HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2020-12-29 US claimed
EP-3038621-A2 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR Human Biomolecular Research Institute (US) 2016-07-06 EP claimed
US-20160038641-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2016-02-11 US claimed
WO-2014146039-A2 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2014-09-18 WO claimed
US-20110045514-A1 METHODS FOR DETECTING MAJOR ADVERSE CARDIOVASCULAR AND CEREBROVASCULAR EVENTS BG MEDICINE, INC. (US) 2011-02-24 US claimed
CN-101939651-A Methods for detecting major adverse cardiovascular and cerebrovascular events BG MEDICINE INC 2011-01-05 CN claimed
EP-2210108-A2 METHODS FOR DETECTING MAJOR ADVERSE CARDIOVASCULAR AND CEREBROVASCULAR EVENTS BG Medicine, Inc. (US) 2010-07-28 EP claimed
CN-101454026-A Novel imaging agents GE HEALTHCARE LTD (GB) 2009-06-10 CN claimed
WO-2009049189-A2 METHODS FOR DETECTING MAJOR ADVERSE CARDIOVASCULAR AND CEREBROVASCULAR EVENTS BG MEDICINE, INC. (US) 2009-04-16 WO claimed
US-20080054171-A1 Target for Laser Desorption/Ionisation Mass Spectrometry PHYSIKALISCHES BURO STEINMULLER GMBH 2008-03-06 US claimed
CN-1187345-C Method for preparing N-[1-(S)-carbethoxy-3-hydrocinnamyl] -L-alanine-N-carboxy acid anhydride AMERICAN YONGGWAN CORP (US) 2005-02-02 CN claimed
CN-1381447-A Method for preparing N-[1-(S)-carbethoxy-3-hydrocinnamyl] -L-alanine-N-carboxy acid anhydride AMERICAN YONGGWAN CORP (US) 2002-11-27 CN claimed
EP-3253752-B1 [9,10-DIMETHOXY-3-(2-METHYLPROPYL)-1H,2H,3H,4H,6H,7H,11BH-PYRIDO-[2,1-A]ISOQUINOLIN-2-YL]METHANOL AND COMPOUNDS, COMPOSITIONS AND METHODS RELATING THERETO NEUROCRINE BIOSCIENCES INC (US) 2023-08-16 EP disclosed
US-11596716-B2 Compounds and matrices for use in bone growth and repair HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2023-03-07 US disclosed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
CN-1381447-A Method for preparing N-[1-(S)-carbethoxy-3-hydrocinnamyl] -L-alanine-N-carboxy acid anhydride AMERICAN YONGGWAN CORP (US) 2002-11-27 CN disclosed
US-5283283-A High modulus blend of poly(α-amino acid) in rubbery elastomer THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-02-01 US disclosed
US-4399149-A Fungicides SHELL OIL COMPANY (US) 1983-08-16 US disclosed
EP-0057027-A2 Fungicides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1982-08-04 EP disclosed