Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529710 | 0.94 | ALDH1A1 (0.54) | ALDH1A1TSHRLMNAESR1TP53 | |
| SCHEMBL11527713 | 0.92 | TSHR (0.53) | ALDH1A1TSHRLMNAESR1TP53 | |
| SCHEMBL11593386 | 0.90 | ESR1 (0.52) | ALDH1A1TSHRLMNAESR1TP53 | |
| SCHEMBL11528226 | 0.88 | TSHR (0.51) | ALDH1A1TSHRLMNAESR1TP53 | |
| SCHEMBL11529785 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNAESR1TP53 | |
| SCHEMBL31296901 | 0.78 | TSHR (0.51) | ALDH1A1TSHRLMNAESR1TP53 | |
| SCHEMBL27932830 | 0.74 | ALDH1A1 (0.53) | ALDH1A1TSHRLMNAESR1TP53 | |
| SCHEMBL11529476 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNAESR1TP53 | |
| SCHEMBL11526322 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNAESR1TP53 | |
| SCHEMBL27932890 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNAESR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132750-A | RING OPENING POLYMERIZATION OF NORBORNENE DERIVATIVES | SHOWA DENKO K.K. (JP) | 1979-01-02 | — | — | US | disclosed |
| US-4028482-A | LOW VISCOSITY POLYALKENAMER | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1977-06-07 | — | — | US | disclosed |