Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 5/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524659 | 1.00 | GRIA2 (0.53) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11621038 | 0.95 | GRIA1 (0.57) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11526595 | 0.85 | GRIA2 (0.58) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11526597 | 0.85 | GRIA2 (0.58) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11525867 | 0.83 | GRIA2 (0.56) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11525860 | 0.83 | GRIA2 (0.56) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL12807824 | 0.82 | GRIA1 (0.54) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL14649680 | 0.81 | HRH3 (0.54) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11524401 | 0.81 | HRH3 (0.54) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11524397 | 0.81 | HRH3 (0.54) | GRIA2GRIA1GRIA3HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |