Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 5/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524934 | 1.00 | GRIA2 (0.45) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL9450875 | 0.96 | GRIA1 (0.48) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL8022460 | 0.88 | GRIA2 (0.37) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL8022463 | 0.88 | GRIA2 (0.37) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL25070381 | 0.86 | GRIA1 (0.45) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11520098 | 0.86 | GRIA2 (0.47) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11520101 | 0.86 | GRIA2 (0.47) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL20343290 | 0.84 | MEN1 (0.52) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL6462682 | 0.84 | MEN1 (0.52) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL6462690 | 0.84 | MEN1 (0.52) | GRIA2GRIA1GRIA3HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |